Mantle cell lymphoma is a rare subtype of non-Hodgkin’s lymphoma with poor prognosis and continue to be challenging to treat. The choice of first line induction regimen remains a topic of debate due paucity of clinical trials. We retrospectively evaluated 66 patients diagnosed with mantle cell lymphoma who achieved first complete response after induction chemotherapy followed by autologous stem cell transplant. Treatment groups were divided into lowintensity versus high-intensity regimens. Our data showed the intensity of induction regimen does not impact posttransplant outcomes of mantle cell lymphoma who underwent autologous stem cell transplant in first complete response.
Albanyan, Omar; Alkassis, Samer; Kim, Seongho; Kin, Andrew; Alavi, Asif; Ayash, Lois; Ratanatharathorn, Voravit; Modi, Dipenkumar; Uberti, Joseph P.; and Deol, Abhinav
"Impact of pre-transplant induction therapy on outcomes of patients who undergo autologous stem cell transplantation for mantle cell lymphoma in first complete remission,"
Hematology/Oncology and Stem Cell Therapy: Vol. 16
, Article 9.
Available at: https://doi.org/10.1016/j.hemonc.2021.07.005